Viagra and Sildenafil. What are they?

Probably every man having difficulties with an erection has tried Viagra. This drug came to the pharmaceutical market more than 20 years ago and created a revolution in the treatment of erectile dysfunction.

Brand Viagra was an indisputable leader until 2017 when the first Viagra generic was released. Containing the same active ingredient, sildenafil citrate, this medication crushed the ratings of brand Viagra sales.

What were the reasons for that? In fact, there was only one reason – the price. Generic Sildenafil is several times cheaper if compared to the brand Viagra pills.

What is Generic Sildenafil?

Generic Sildenafil is a medication targeted at the treatment of erectile dysfunction. Generics are the drugs possessing the same pharmacological properties as the brand medications. Their composition, mechanism of action, the amounts of the active ingredient, onset of action, safety, and other effects are identical to those of the brand counterpart.

The difference between them lies in the legal field. Unlike brand Viagra pills, which took millions of investments on each stage of its development, studies, branding, and patenting, generic Sildenafil didn’t need to go through all those stages. Therefore, the only investment made by its manufacturers is the purchase of the drug formula after the brand patent has expired.

The other differences between brand Viagra and generic Sildenafil are the manufacturer, the appearance of the pill, and the package. Brand Viagra is produced by Pfizer, whereas generic Sildenafil is a product of many other pharmaceutical companies whose production facilities are based in India and other developing countries.

Due to such a location, Sildenafil manufacturers can save additional funds. The taxes in India are much lower than in the US. The level of remuneration of the company workers in India is significantly lower as well.

A combination of the listed above factors makes the price of generic Sildenafil more affordable for the users, leaving brand medication behind.

Sildenafil vs Viagra. How They Work?

There’s nothing to compare in Sildenafil vs Viagra mechanism of action as both medications contain the same active component – sildenafil citrate. Therefore, they work exactly the same.

Sildenafil citrate is a drug from the class of PDE5 inhibitors. It blocks the secretion of phosphodiesterase type 5 in the cells of the penile tissues, which allows the growth of the levels of cGMP – the chemical responsible for the widening of the penile blood vessels and the relaxation of the cavernous bodies of the penis.

Viagra vs Sildenafil

To trigger the production of cGMP and another important constituent of this process – nitric oxide, a man has to feel sexual arousal and get sexually stimulated. Only when this condition is fulfilled, sildenafil can start working. The medication increases the inflow of blood to the penis, providing a firm and lasting erection.

As soon as sexual intercourse is over, the erection fades, and the organ gets back to its normal size. The whole process looks absolutely natural, so if a man wants to keep his sensitive problem secret from the partner, Viagra can give him such a possibility.

Viagra vs Sildenafil. Medicinal Forms and Dosages

Viagra by Pfizer is produced in the form of the pills. It’s not rare that brand Viagra is called “the blue pill”. Its diamond-shaped form and color became as recognizable as the medication itself.

Generic Sildenafil offers its users a wider choice of forms; starting with the classic tablet form, generic Sildenafil is also available in sublingual pills, chewable tablets, oral jelly, and even oral spray.

Men are free to choose the one they like most. Chewable tablets and oral jelly, they come in different flavors.

Viagra pills are produced in three dosage strengths: 25 mg, 50 mg, and 100 mg. Most Sildenafil generics come in 100 mg dosage strength, but there are also medications containing 18.38 mg/ml (oral spray), 25 mg, 50 mg, 120 mg, 130 mg, 150 mg, and 200 mg of sildenafil citrate.

The maximum recommended daily dose is 100 mg and any increase in the dosing regimen should be agreed with a specialist.

How to take Viagra and Sildenafil?

The tablet form of both brand and generic medications needs about an hour to start working. The shortest period from the drug intake until the onset of the effects is 30 minutes. A maximum time can be up to two hours.

The time Viagra or Sildenafil needs to come into effect depends on the patient’s age, health condition, the severity of ED, intake of other medications, the dose administered, and the response to the drug.

Generic Sildenafil in the form of chewable tablets, sublingual pills, oral jelly, and oral spray work faster. You can attain a firm erection in about 15 – 30 minutes after the intake. Still, all the manufacturers recommend using the medication, regardless if it is brand Viagra or generic Sildenafil, about 60 minutes before anticipated sexual intercourse.

Avoid eating fatty food, as it will delay the onset of action of the pill. The duration of action of Viagra and Sildenafil varies from four to five hours. If low doses are used, the effect may withdraw sooner.