The General Notion on Viagra

Almost every man leading an active sexual life faced with some issues connected with the loss of erection in the middle of intercourse. Some men can’t even attain an erection to start coitus. Such occasional failures can be the first bells of upcoming erectile dysfunction. It means that you still have time to change your style of life, improve your health and escape real problems.

Those who already don’t have a chance to prevent ED should try Viagra. This medication became a real revolution in the treatment of poor erection back in 1998 when it first came to the drugstore shelves.

Now, Viagra and its countless generics continue helping men suffering from erectile dysfunction provoked by diabetes, hypertension, atherosclerosis, depression. This medication is a real panacea for such patients.

Unfortunately, there exists no treatment that can cure ED once and for all, but Viagra can effectively deal with the issue at least temporarily.

Viagra Mechanism of Action

Unlike other medications that don’t need any additional conditions to start working, Viagra is a drug that comes into effect only if a man feels sexual arousal or gets sexually stimulated.

The General Notion on Viagra

Fulfilling this condition is crucial as it triggers the onset of Viagra’s action. The thing is that under sexual stimulation of the male sex organ, nitric oxide is released. The production of nitric oxide triggers the secretion of cGMP, which helps the relaxation of the smooth muscle tissue in the arteries and penis. As a result, the organ can fill with enough blood to erect.

Viagra belongs to the class of PDE5 inhibitors. Phosphodiesterase type 5 breaks down cGMP, and thus prevents the relaxation of the muscles. By inhibiting the secretion of PDE5, Viagra prolongs the duration of the erection, which allows men to have healthy sexual intercourse.

Viagra Onset of Action

The main question for men who only start the treatment with Viagra is how long for Viagra to work. In fact, the answer depends on the medical form of the drug you use. Brand Viagra is produced in the tablet form only. Generics are also available in the form of oral jelly, chewable tablets, sublingual pills, oral spray. There even exist Viagra topical gel, but its efficiency is still being studied.

So let’s have a look at the time needed for different forms of the drug to work:

  • Viagra tablets need from 30 minutes to an hour to come into effect. Some men may be able to attain an erection in 20 minutes, but some may need to wait for about two hours. It mostly depends on the patient’s response to the medication.
  • Viagra oral jelly. This one needs from 20 to 30 minutes to start working. But again, in some cases, it may need more time.
  • Viagra sublingual pills. Due to the way this form of Viagra is absorbed, it already works in 15 minutes after the intake.
  • Viagra chewable tablets. The manufacturer recommends taking this form of the drug about an hour before anticipated sexual activity. Still, the users claim that chewable tablets start working faster, approximately 15 minutes after the intake.

Food can delay the onset of action of Viagra oral tablets and oral jelly, but it has no impact on the onset of action of the other medical forms of the drug. Therefore, to guarantee a fast effect of Viagra, you should take it on an empty stomach.

Viagra Duration of Action

There doesn’t exist a single answer to the question of how long does Viagra stay in your system. The duration of its effect depends on several factors including:

  • The dosage strength you use. Low doses, like 25 gm, withdraw faster if compared to the highest recommended dosage, which is 100 mg.
  • Individual peculiarities of the patient. Age, weight, and the speed of metabolic processes have a great impact on Viagra’s duration of action. For example, Viagra stays longer in the body of a man, aged more than 65, if compared to a man, aged 40 because of the differences in their metabolism.
  • General health condition. Viagra excretes with the feces and urine. In case your kidneys or liver don’t work properly, the drug may stay in the body longer.
  • Other medicines intake. Some medications can slow down the metabolism of sildenafil thus increasing the time of its presence in the body.

Getting back to the question of how long Viagra lasts it should be said that the common period of Viagra effectiveness is 4 – 5 hours. However, the scientists described the cases when Viagra remained effective for about 12 hours after the intake.

The shortest period of Viagra efficiency is between three and four hours. However, it is not a reason to get disappointed. One of the benefits of using Viagra is that it shortens the refractory period (it is the time needed for a man to restore after the ejaculation). Therefore, even if the drug will stay effective for only three hours, you still have the possibility to perform two or three sexual intercourses.