Viagra – a Potent Weapon against ED

Loss of male power is a problem that affects about 70% of men. In some countries, this figure reaches up to 90%. Such poor statistics is a clear demonstration of how important Viagra is. This drug is potent enough to help men with different levels of severity of erectile dysfunction restore their ability to have a normal-duration sexual activity.

Viagra is effective for the sexual inability caused by both physical and psychological factors. This medication is often prescribed in men, whose erectile dysfunction is associated with diabetes, neurological diseases and injuries, hypertension, cardiovascular health issues, obesity. Viagra tends to be effective for ED provoked by other medications intake, depression, and harmful habits.

What is the secret of such effectiveness? What exactly does Viagra do? Let’s find out!

How Viagra Works

This medication belongs to the class of PDE5 inhibitors. It means that Viagra inhibits the production of phosphodiesterase type 5 – the chemical, which breaks down cGMP – an enzyme responsible for the relaxation of the muscular tissue of the blood vessels and penis.

cGMP is produced in the human cells under the impact of nitric oxide, which is released in the tissues of the male sex organ when a man feels sexually excited or is sexually stimulated.

Under the influence of nitric oxide and cGMP, the blood vessels leading to the penile area, widen allowing more blood to get to the penis. The other constituents of a healthy erection are the cavernous bodies of the penis. They are sponge-like tissue that holds most of the blood coming to the penis during an erection. Viagra helps their relaxation and, thus they can fill with enough blood to attain an erection.

Viagra Effect on BPH

It’s not rare that erectile dysfunction in men is caused by the problems with a prostate gland, benign prostatic hyperplasia being one of the most common. Years of clinical studies and use by the patients have made the doctors think about the benefits of Viagra, and its active ingredient sildenafil citrate in particular, about the benefits of this medication for the treatment of BPH.

Even though Viagra is not yet approved for the treatment of this disease, it is often used off-label to reduce lower urinary tract symptoms in men suffering from the enlarged prostate. So how does Viagra work for BPH?

The effectiveness of Viagra is associated with the relaxation of the prostate gland and bladder tissues it induces. Due to the relaxation of the muscles, the lumen of the urethra widens which eases the flow of the urine from the bladder and helps to reduce such lower urinary tract symptoms as:

  • A weak stream of the urine;
  • Dribbling;
  • The feeling of incomplete bladder emptying.

Such positive effects on the BPH symptoms don’t reduce the efficiency of Viagra in the treatment of ED. Therefore, men suffering from both BPH and erectile dysfunction can get a double benefit from a single drug.

How to Use Viagra?

To make the treatment with Viagra both effective and safe, it is important to choose the right dosage of the medication. If you have never used any ED drugs before, it is better to start with a 50 mg dose to understand how Viagra works for you. If you are satisfied with the effect and don’t have any unwanted reactions (e.g. a headache, nasal stuffiness, flushing), stick to this dose.

In case the erection was weak or didn’t last long enough to finish sexual intercourse, increase the dose to 100 mg. This is the highest recommended dose of Viagra. On the contrary, if the effect of the drug appeared to be too strong, or you experienced some side effects, reduce the dose to 25 mg.

Viagra is not a drug for scheduled intake. You should take it only when you plan sexual intercourse. The medication needs about an hour to come into effect, though in some men it may start working in already 30 minutes.

Generic Viagra is produced in different medical forms, which allow the drug to work faster. The manufacturers claim that generic Viagra sublingual and chewable tablets, as well as Viagra oral spray, can come into effect in 15 minutes after the intake.

You shouldn’t take more than one Viagra pill per day. If you need to take the drug for two or more days in a row, there should be at least 24 hours between the pills intake.

Viagra Interactions. How Viagra Works

It is known how Viagra works. The way Viagra works can be affected by the use of other medicines. Some drugs can get into hazardous interactions with Viagra. One of such preparations are nitrates, which are often used to treat heart health issues.

How Viagra Works

Concomitant intake of nitrates and Viagra can result in a severe drop in blood pressure. It can be difficult to stabilize and potentially lead to death. The same danger lies in the use of “poppers” recreational drugs containing nitrites.

Alpha-blockers can also exacerbate the blood-pressure-lowering effect of Viagra and lead to dizziness and fainting.

Azole antifungals, HIV protease inhibitors, as well as macrolide antibiotics, can slow down the clearance of sildenafil from the body, thus increasing the risks for side effects.